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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-EFNB3 antibody (28-226) (STJ23485)

  • 產(chǎn)品型號(hào)：STJ23485
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Anti-EFNB3 antibody (28-226) (STJ23485)
詳情介紹：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-EFNB3 (28-226) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:4000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EFNB3
Gene ID: 1949
Uniprot ID: EFNB3_HUMAN
Immunogen Region: 28-226
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 28-226 of human EFNB3 (NP_001397.1).
Immunogen Sequence: LSLEPVYWNSANKRFQAEGG YVLYPQIGDRLDLLCPRARP PGPHSSPNYEFYKLYLVGGA QGRRCEAPPAPNLLLTCDRP DLDLRFTIKFQEYSPNLWGH EFRSHHDYYIIATSDGTREG LESLQGGVCLTRGMKVLLRV GQSPRGGAVPRKPVSEMPME RDRGAAHSLEPGKENLPGDP TSNATSRGAEGPLPPPSMP
Tissue Specificity Highly expressed in brain.expressed in embryonic floor plate, roof plate and hindbrain segments.
Function Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons. (Microbial infection) Acts as a receptor for nipah virus and hendra virus.
Protein Name Ephrin-B3
Eph-Related Receptor Transmembrane Ligand Elk-L3
Eph-Related Receptor Tyrosine Kinase Ligand 8
Lerk-8
Database Links Reactome: R-HSA-2682334
Reactome: R-HSA-3928662
Reactome: R-HSA-3928664
Reactome: R-HSA-3928665
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Ephrin-B3 antibody
Anti-Eph-Related Receptor Transmembrane Ligand Elk-L3 antibody
Anti-Eph-Related Receptor Tyrosine Kinase Ligand 8 antibody
Anti-Lerk-8 antibody
Anti-EFNB3 antibody
Anti-EPLG8 antibody
Anti-LERK8 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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