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產(chǎn)品詳情

  • 產(chǎn)品名稱：Mouse MEPE (Matrix Extracellular Phosphoglycoprotein) Sandwich ELISA Kit (STJE0010559)

  • 產(chǎn)品型號(hào)：STJE0010559
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Mouse MEPE (Matrix Extracellular Phosphoglycoprotein) Sandwich ELISA Kit (STJE0010559)
詳情介紹：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.22ng/mL
Detection Limit: 0.468-30ng/mL
Short Description: This MEPE Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Mepe
Gene ID: 94111
Uniprot ID: MEPE_MOUSE
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity Expressed in osteocytes (at protein level). Expressed by chondrocytes, specifically in the hypertrophic zone of the bone growth plate (at protein level). Expressed in osteoblasts in bone (at protein level). Expressed by osteoblasts within the metaphysis (at protein level). Expressed at low levels in white fat, brown fat, testes, brain and aorta. Expressed in the craniofacial complex (at protein level). Expressed in odontoblasts, ameloblasts and in predentin during tooth development (at protein level). Expressed in the kidney (at protein level). Expressed in osteocytes in mandibular condylar cartilage and tibial cartilage (at protein level). Expressed in salivary glands.
Post Translational Modifications Phosphorylated on serine residues in the ASARM motif.the phosphorylation is important for the inhibition of bone mineralization. Cleaved by CTSB/cathepsin B.the cleavage is blocked by metalloprotease PHEX.
Function Regulates renal phosphate and uric acid excretion. Regulates bone mineralization by osteoblasts and cartilage mineralization by chondrocytes. Regulates the mineralization of the extracellular matrix of the craniofacial complex, such as teeth, bone and cartilage. Increases dental pulp stem cell proliferation.
Protein Name Matrix Extracellular Phosphoglycoprotein
Osteoblast/Osteocyte Factor 45
Of45
Osteoregulin
Database Links Reactome: R-MMU-381426
Reactome: -MMU-8957275
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative ELISA Names Matrix Extracellular Phosphoglycoprotein ELISA kit
Osteoblast/Osteocyte Factor 45 ELISA kit
Of45 ELISA kit
Osteoregulin ELISA kit
Mepe ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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