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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-ADA antibody (50-100) {FITC} (STJ506025)

  • 產(chǎn)品型號(hào)：STJ506025-100
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Anti-ADA antibody (50-100) {FITC} (STJ506025)
詳情介紹：
Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ADA (50-100) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: FITC
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5-1.5 μg/μl
Dilution Range: WB: 1:50
ELISA: 1:50, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ADA
Gene ID: 100
Uniprot ID: ADA_HUMAN
Immunogen Region: 50-100
Immunogen: Synthetic peptide taken within amino acid region 50-100 on human Adenosine Deaminase/Adenosine Aminohydrolase.
Tissue Specificity Found in all tissues, occurs in large amounts in T-lymphocytes. Expressed at the time of weaning in gastrointestinal tissues.
Function Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion. Enhances dendritic cell immunogenicity by affecting dendritic cell costimulatory molecule expression and cytokines and chemokines secretion. Enhances CD4+ T-cell differentiation and proliferation. Acts as a positive modulator of adenosine receptors ADORA1 and ADORA2A, by enhancing their ligand affinity via conformational change. Stimulates plasminogen activation. Plays a role in male fertility. Plays a protective role in early postimplantation embryonic development.
Protein Name Adenosine Deaminase
Adenosine Aminohydrolase
Database Links Reactome: R-HSA-74217
Reactome: R-HSA-9734735
Reactome: R-HSA-9755088
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Extracellular Side
Cell Junction
Cytoplasmic Vesicle Lumen
Cytoplasm
Lysosome
Colocalized With Dpp4 At The Cell Surface
Alternative Antibody Names Anti-Adenosine Deaminase antibody
Anti-Adenosine Aminohydrolase antibody
Anti-ADA antibody
Anti-ADA1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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