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產(chǎn)品名稱：Ephrin Receptor A1 Positive Control peptide (STJ505304)
產(chǎn)品型號：STJ505304-5
產(chǎn)品廠商：ST john's laboratory
產(chǎn)品文檔：

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簡單介紹：

Ephrin Receptor A1 Positive Control peptide (STJ505304)

詳情介紹：

Applications:	WB
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Ephrin Receptor A1 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.

Formulation:	Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range:	WB: 1:500
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	EPHA1
Gene ID:	2041
Uniprot ID:	EPHA1_HUMAN

Tissue Specificity	Overexpressed in several carcinomas.
Post Translational Modifications	Phosphorylated. Autophosphorylation is stimulated by its ligand EFNA1. Ubiquitinated.
Function	Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Also plays a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.
Peptide Name	Ephrin Type-A Receptor 1 Hepha1 Eph Tyrosine Kinase Eph Tyrosine Kinase 1 Erythropoietin-Producing Hepatoma Receptor Tyrosine-Protein Kinase Receptor Eph
Database Links	Reactome: R-HSA-2682334 Reactome: R-HSA-2892247 Reactome: R-HSA-3928663 Reactome: R-HSA-3928665
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Peptide Names	Ephrin Type-A Receptor 1 protein Hepha1 protein Eph Tyrosine Kinase protein Eph Tyrosine Kinase 1 protein Erythropoietin-Producing Hepatoma Receptor protein Tyrosine-Protein Kinase Receptor Eph protein EPHA1 protein EPH protein EPHT protein EPHT1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產(chǎn)品名稱：Ephrin Receptor A1 Positive Control peptide (STJ505304)