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簡單介紹：

Human Fc epsilon RII/CD23 protein (Recombinant) (N-his) (STJP001400)

詳情介紹：

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human Fc epsilon RII/CD23-N-his protein was developed from hek293 cells and has a target region of N-his. For use in research applications.

Formulation:

Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.

Gene Symbol:	FCER2
Gene ID:	2208
Uniprot ID:	FCER2_HUMAN
Immunogen:	Recombinant Human Fc epsilon RII/CD23 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp 48-Ser321) of human CD23/Fc epsilon RII (Accession #NP_001993.2.) fused with a 6×His tag at the N-terminus

Function	Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway.
Protein Name	Low Affinity Immunoglobulin Epsilon Fc Receptor Blast-2 C-Type Lectin Domain Family 4 Member J Fc-Epsilon-Rii Immunoglobulin E-Binding Factor Lymphocyte Ige Receptor Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form
Database Links	Reactome: R-HSA-2197563 Reactome: R-HSA-6783783 Reactome: R-HSA-6785807
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein Lipid-Anchor Secreted Also Exists As A Soluble Excreted Form Scd23
Alternative Protein Names	Low Affinity Immunoglobulin Epsilon Fc Receptor protein Blast-2 protein C-Type Lectin Domain Family 4 Member J protein Fc-Epsilon-Rii protein Immunoglobulin E-Binding Factor protein Lymphocyte Ige Receptor protein Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form protein FCER2 protein CD23A protein CLEC4J protein FCE2 protein IGEBF protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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