產品詳情
簡單介紹:
Human Ephrin-A4/EFNA4 protein (Recombinant) (C-hFc & His) (STJP002581)
詳情介紹:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Ephrin-A4/EFNA4-C-hFc & His protein was developed from hek293 cells and has a target region of C-hFc & His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human EphA7 at 0.5 Mu g/mL (100 Mu L/well) can bind Human EFNA4 with a linear range of 0.039-0.942 ng/mL. |
Gene Symbol: | EFNA4 |
Gene ID: | 1945 |
Uniprot ID: | EFNA4_HUMAN |
Immunogen Region: | Leu26-Gly171 |
Immunogen: | Recombinant Human Ephrin-A4/EFNA4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu26-Gly171) of human Ephrin-A4/EFNA4 (Accession # NP_005218.1) fused with an Fc, 6×His tag at the C-terminus. |
Function | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils. |
Protein Name | Ephrin-A4 Eph-Related Receptor Tyrosine Kinase Ligand 4 Lerk-4 |
Database Links | Reactome: R-HSA-2682334 Reactome: R-HSA-3928663 Reactome: R-HSA-3928665 |
Cellular Localisation | Isoform 1: Cell Membrane Lipid-Anchor Gpi-Anchor Isoform 2: Secreted |
Alternative Protein Names | Ephrin-A4 protein Eph-Related Receptor Tyrosine Kinase Ligand 4 protein Lerk-4 protein EFNA4 protein EPLG4 protein LERK4 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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