產(chǎn)品詳情
簡單介紹：
human Ephrin-A3/EFNA3 protein (Recombinant) (C-6His) (STJP001894)
詳情介紹：
| Host: | HEK293 cells |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Recombinant-human Ephrin-A3/EFNA3-C-6His protein was developed from hek293 cells and has a target region of C-6His. For use in research applications. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EFNA3 |
| Gene ID: | 1944 |
| Uniprot ID: | EFNA3_HUMAN |
| Immunogen Region: | Met 1-Ser 213 |
| Immunogen: | Recombinant human Ephrin-A3/EFNA3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met 1-Ser 213) of human Ephrin-A3/EFNA3 (Accession #NP_004943.1.) fused with and a 6×His tag at the C-terminus. |
| Function | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. |
| Protein Name | Ephrin-A3 Efl-2 Ehk1 Ligand Ehk1-L Eph-Related Receptor Tyrosine Kinase Ligand 3 Lerk-3 |
| Database Links | Reactome: R-HSA-2682334 Reactome: R-HSA-3928663 Reactome: R-HSA-3928665 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor |
| Alternative Protein Names | Ephrin-A3 protein Efl-2 protein Ehk1 Ligand protein Ehk1-L protein Eph-Related Receptor Tyrosine Kinase Ligand 3 protein Lerk-3 protein EFNA3 protein EFL2 protein EPLG3 protein LERK3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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