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產(chǎn)品名稱：Human Ep-CAM/TROP-1/CD326 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002228)
產(chǎn)品型號：STJP002228-100
產(chǎn)品廠商：ST john's laboratory
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Human Ep-CAM/TROP-1/CD326 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002228)

詳情介紹：

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human Ep-CAM/TROP-1/CD326-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications.

Conjugation:	Biotin
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Endotoxin:	Less than 1EU per Mu g by the LAL method.

Gene Symbol:	EPCAM
Gene ID:	4072
Uniprot ID:	EPCAM_HUMAN
Immunogen Region:	Gln24-Lys245
Immunogen:	Recombinant Biotinylated Human EpCAM/TROP1 Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal.；It contains Gln24-Lys245.

Post Translational Modifications	Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability.
Function	May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Protein Name	Epithelial Cell Adhesion Molecule Ep-Cam Adenocarcinoma-Associated Antigen Cell Surface Glycoprotein Trop-1 Epithelial Cell Surface Antigen Epithelial Glycoprotein Egp Epithelial Glycoprotein 314 Egp314 Hegp314 Ks 1/4 Antigen Ksa Major Gastrointestinal Tumor-Associated Protein Ga733-2 Tumor-Associated Calcium Signal Transducer 1 Cd Antigen Cd326
Database Links	Reactome: R-HSA-202733
Cellular Localisation	Lateral Cell Membrane Single-Pass Type I Membrane Protein Cell Junction Tight Junction Colocalizes With Cldn7 At The Lateral Cell Membrane And Tight Junction
Alternative Protein Names	Epithelial Cell Adhesion Molecule protein Ep-Cam protein Adenocarcinoma-Associated Antigen protein Cell Surface Glycoprotein Trop-1 protein Epithelial Cell Surface Antigen protein Epithelial Glycoprotein Egp protein Epithelial Glycoprotein 314 protein Egp314 protein Hegp314 protein Ks 1/4 Antigen protein Ksa protein Major Gastrointestinal Tumor-Associated Protein Ga733-2 protein Tumor-Associated Calcium Signal Transducer 1 protein Cd Antigen Cd326 protein EPCAM protein GA733-2 protein M1S2 protein M4S1 protein MIC18 protein TACSTD1 protein TROP1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產(chǎn)品名稱：Human Ep-CAM/TROP-1/CD326 protein (Recombinant) (C-His &amp; Avi) {Biotin} (STJP002228)

產(chǎn)品名稱：Human Ep-CAM/TROP-1/CD326 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002228)