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產(chǎn)品詳情

  • 產(chǎn)品名稱：Human CD80 (B7-1) protein (Recombinant) (STJP000516)

  • 產(chǎn)品型號(hào)：STJP000516
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Human CD80 (B7-1) protein (Recombinant) (STJP000516)
詳情介紹：
Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human CD80 (B7-1)-protein was developed from hek293. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilised from 0.2um filtered 50mM Tris, 100mM NaCl, pH 8.0.
Storage Instruction: Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/μg (1EU/μg). NA
Gene Symbol: CD80
Gene ID: 941
Uniprot ID: CD80_HUMAN
Immunogen Region: ECD
Immunogen: Optimized DNA sequence encoding Human extracellular domain of human CD80including a C-terminal 6His tag was expressed in HEK293 cells. NA
Tissue Specificity Expressed on activated B-cells, macrophages and dendritic cells.
Function Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. (Microbial infection) Acts as a receptor for adenovirus subgroup B.
Protein Name T-Lymphocyte Activation Antigen Cd80
Activation B7-1 Antigen
Bb1
Ctla-4 Counter-Receptor B7.1
B7
Cd Antigen Cd80
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-2219530
Reactome: R-HSA-389356
Reactome: R-HSA-389357
Reactome: R-HSA-389359
Reactome: R-HSA-389513
Reactome: R-HSA-6783783
Reactome: R-HSA-6811558
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names T-Lymphocyte Activation Antigen Cd80 protein
Activation B7-1 Antigen protein
Bb1 protein
Ctla-4 Counter-Receptor B7.1 protein
B7 protein
Cd Antigen Cd80 protein
CD80 protein
CD28LG protein
CD28LG1 protein
LAB7 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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