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產(chǎn)品名稱(chēng)：Human CD40/TNFRSF5 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001556)
產(chǎn)品型號(hào)：STJP001556
產(chǎn)品廠商：ST john's laboratory
產(chǎn)品文檔：

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Human CD40/TNFRSF5 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001556)

詳情介紹：

Host:	HEK293
Note:	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human CD40/TNFRSF5-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.

Conjugation:	Biotin
Formulation:	Lyophilised from 0.2 μm filtered PBS solution pH7.4.
Dilution Range:	Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction:	The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin:	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/μg (1EU/μg).

Gene Symbol:	CD40
Gene ID:	958
Uniprot ID:	TNR5_HUMAN
Immunogen Region:	Glu21-Arg193
Immunogen:	DNA sequence encoding Human CD40/TNFRSF5 including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.

Function	Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Protein Name	Tumor Necrosis Factor Receptor Superfamily Member 5 B-Cell Surface Antigen Cd40 Bp50 Cd40l Receptor Cdw40 Cd Antigen Cd40
Database Links	Reactome: R-HSA-198933 P25942-1 Reactome: R-HSA-5668541 P25942-1 Reactome: R-HSA-5676594 P25942-1
Cellular Localisation	Isoform I: Cell Membrane Single-Pass Type I Membrane Protein Isoform Ii: Secreted
Alternative Protein Names	Tumor Necrosis Factor Receptor Superfamily Member 5 protein B-Cell Surface Antigen Cd40 protein Bp50 protein Cd40l Receptor protein Cdw40 protein Cd Antigen Cd40 protein CD40 protein TNFRSF5 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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