產(chǎn)品詳情
簡單介紹：
CCR3 Blocking Peptide peptide (STJ503783)
詳情介紹：
| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | CCR3 Blocking Peptide is synthetically produced from the 1-50 aa sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | CCR3 |
| Gene ID: | 1232 |
| Uniprot ID: | CCR3_HUMAN |
| Immunogen Region: | 1-50 aa |
| Immunogen: | Synthetic peptide taken within amino acid region 1-50 on human CCR3 protein. |
| Tissue Specificity | In eosinophils as well as trace amounts in neutrophils and monocytes. |
| Function | Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection. |
| Peptide Name | C-C Chemokine Receptor Type 3 C C Ckr3 C-C Ckr-3 Cc-Ckr-3 Ccr-3 Ccr3 Ckr 3 Ckr3 Eosinophil Eotaxin Receptor Cd Antigen Cd193 |
| Database Links | Reactome: R-HSA-380108 Reactome: R-HSA-418594 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
| Alternative Peptide Names | C-C Chemokine Receptor Type 3 protein C C Ckr3 protein C-C Ckr-3 protein Cc-Ckr-3 protein Ccr-3 protein Ccr3 protein Ckr 3 protein Ckr3 protein Eosinophil Eotaxin Receptor protein Cd Antigen Cd193 protein CCR3 protein CMKBR3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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