產(chǎn)品詳情
簡單介紹:
ELOVL1 Positive Control for STJ500870 peptide (STJ505289)
詳情介紹:
Applications: | WB |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | ELOVL1 Positive Control for STJ500870 is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Dilution Range: | WB: 1:500 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | ELOVL1 |
Gene ID: | 64834 |
Uniprot ID: | ELOV1_HUMAN |
Specificity: | This is positive control is recommended for use in combination with ELOVL1 antibody STJ500870. |
Tissue Specificity | Ubiquitous. |
Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and monounsaturated acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs. |
Peptide Name | Elongation Of Very Long Chain Fatty Acids Protein 1 3-Keto Acyl-Coa Synthase Elovl1 Elovl Fatty Acid Elongase 1 Elovl Fa Elongase 1 Very Long Chain 3-Ketoacyl-Coa Synthase 1 Very Long Chain 3-Oxoacyl-Coa Synthase 1 |
Database Links | Reactome: R-HSA-2046105 Reactome: R-HSA-2046106 Reactome: R-HSA-75876 |
Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein |
Alternative Peptide Names | Elongation Of Very Long Chain Fatty Acids Protein 1 protein 3-Keto Acyl-Coa Synthase Elovl1 protein Elovl Fatty Acid Elongase 1 protein Elovl Fa Elongase 1 protein Very Long Chain 3-Ketoacyl-Coa Synthase 1 protein Very Long Chain 3-Oxoacyl-Coa Synthase 1 protein ELOVL1 protein SSC1 protein CGI-88 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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