產(chǎn)品詳情
簡單介紹：
Human Fc-gamma RIIb/CD32b protein (Recombinant) (C-His) (STJP000851)
詳情介紹：
| Host: | HEK293 cells |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Recombinant-Human Fc-gamma RIIb/CD32b-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human FCGR2B at 2 Mu g/mL (100 Mu L/well) can bind biotinylated Human IgG1 with a linear range of 0.0048-2.81 Mu g/mL.2. Measured by its binding ability in a functional EL |
| Gene Symbol: | FCGR2B |
| Gene ID: | 2213 |
| Uniprot ID: | FCG2B_HUMAN |
| Immunogen: | Recombinant Human Fc-gamma RIIb/CD32b Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala46-Pro217) of human Fc gamma RIIB/C (Accession #NP_003992.3) fused with a 6×His tag at the C-terminus. |
| Tissue Specificity | Is the most broadly distributed Fc-gamma-receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells. |
| Post Translational Modifications | Phosphorylated by the SRC-type Tyr-kinases LYN and BLK. |
| Function | Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. |
| Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-B Igg Fc Receptor Ii-B Cdw32 Fc-Gamma Rii-B Fc-Gamma-Riib Fcrii-B Cd Antigen Cd32 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative Protein Names | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-B protein Igg Fc Receptor Ii-B protein Cdw32 protein Fc-Gamma Rii-B protein Fc-Gamma-Riib protein Fcrii-B protein Cd Antigen Cd32 protein FCGR2B protein CD32 protein FCG2 protein IGFR2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
相關(guān)信息
![Anti-14-3-3 beta/Theta antibody (1-100) [S1MR] (STJ11103651)](http://y1.yzimgs.com/uploads/465546/2024520-20551366.png?imageView2/2/w/200/h/200)
- 細(xì)胞培養(yǎng)玄學(xué)-MRC-5細(xì)胞 2025-01-07
- Ocean NanoTech定制的詳細(xì)步驟 2021-10-31
- Abbiotec代理的產(chǎn)品得到重復(fù)驗(yàn)證2020 2021-10-31
- click chemistry tools數(shù)據(jù)結(jié)果比... 2021-10-31
- LaysanBio代理商相關(guān)文獻(xiàn)資料2020 2021-10-31
- zyagen Laboratories代理的產(chǎn)品得到... 2021-06-20
- Toxin Technologies代理商相關(guān)文獻(xiàn)資... 2021-03-14
- 熱烈祝賀玉博生物正式代理biocolor公司試劑產(chǎn)品... 2021-03-14
- 熱烈祝賀玉博生物正式代理cytognos公司試劑產(chǎn)品... 2021-03-14
- Gelest代理的產(chǎn)品得到重復(fù)驗(yàn)證2020 2021-03-14
