產(chǎn)品詳情
簡單介紹:
Human Fc-gamma RIIa/CD32a (H167R) protein (Recombinant) (C-hFc & His) (STJP002756)
詳情介紹:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Fc-gamma RIIa/CD32a (H167R)-C-hFc & His protein was developed from hek293 cells and has a target region of C-hFc & His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human FCGR2A/CD32a (R167) at 1 Mu g/mL (100 Mu L/well) can bind FCGR2A Rabbit polyclonal antibody with a linear range of 0.977-175.35 ng/mL. |
Gene Symbol: | FCGR2A |
Gene ID: | 2212 |
Uniprot ID: | FCG2A_HUMAN |
Immunogen Region: | Ala36-Ile218 |
Immunogen: | Recombinant Human Fc-gamma RIIa/CD32a (H167R) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala36-Ile218 (R167) ) of human FCGR2A/CD32a (R167) (Accession #NP_001129691.1) fused with a Fc, 6×His |
Post Translational Modifications | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK. |
Function | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. |
Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A Igg Fc Receptor Ii-A Cdw32 Fc-Gamma Rii-A Fc-Gamma-Riia Fcrii-A Cd Antigen Cd32 |
Database Links | Reactome: R-HSA-2029481 Reactome: R-HSA-2029482 Reactome: R-HSA-2029485 Reactome: R-HSA-6798695 Reactome: R-HSA-9664323 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A protein Igg Fc Receptor Ii-A protein Cdw32 protein Fc-Gamma Rii-A protein Fc-Gamma-Riia protein Fcrii-A protein Cd Antigen Cd32 protein FCGR2A protein CD32 protein FCG2 protein FCGR2A1 protein IGFR2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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