產(chǎn)品詳情
簡單介紹：
Human Fc-gamma RI/CD64 protein (Recombinant) (C-His) (STJP001241)
詳情介紹：
| Host: | HEK293 cells |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Recombinant-Human Fc-gamma RI/CD64-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human FCGR1A, His Tag at 2 Mu g/mL (100 Mu L/well) can bind Rituximab with a linear range of 15.625-58.38 ng/mL. |
| Gene Symbol: | FCGR1A |
| Gene ID: | 2209 |
| Uniprot ID: | FCGR1_HUMAN |
| Immunogen: | Recombinant Human Fc-gamma RI/CD64 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Pro288) of human Fc gamma RI/CD64 (Accession #NP_000557.1) fused with a 6×His tag at the C-terminus. |
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells. |
| Protein Name | High Affinity Immunoglobulin Gamma Fc Receptor I Igg Fc Receptor I Fc-Gamma Ri Fcri Fc-Gamma Ria Fcgammaria Cd Antigen Cd64 |
| Database Links | Reactome: R-HSA-1236978 Reactome: R-HSA-198933 Reactome: R-HSA-2029481 Reactome: R-HSA-2029482 Reactome: R-HSA-2029485 Reactome: R-HSA-877300 Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein Stabilized At The Cell Membrane Through Interaction With Fcer1g |
| Alternative Protein Names | High Affinity Immunoglobulin Gamma Fc Receptor I protein Igg Fc Receptor I protein Fc-Gamma Ri protein Fcri protein Fc-Gamma Ria protein Fcgammaria protein Cd Antigen Cd64 protein FCGR1A protein FCG1 protein FCGR1 protein IGFR1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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