產(chǎn)品詳情
簡(jiǎn)單介紹：
Human Erythropoietin/EPO protein (Recombinant) (C-His) (STJP001526)
詳情介紹：
| Host: | HEK293 cells |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Recombinant-Human Erythropoietin/EPO-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human EPO Protein at 5 Mu g/mL (100 Mu L/well) can bind EPOR with a linear range of 0.12-23.83 ng/mL.2. Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. |
| Gene Symbol: | EPO |
| Gene ID: | 2056 |
| Uniprot ID: | EPO_HUMAN |
| Immunogen: | Recombinant Human Erythropoietin/EPO Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala28-Arg193) of human Erythropoietin/EPO (Accession #NP_000790.2) fused with a 6×His tag at the C-terminus. |
| Function | Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. |
| Protein Name | Erythropoietin Epoetin |
| Database Links | Reactome: R-HSA-1234158 Reactome: R-HSA-9006335 Reactome: R-HSA-9027276 Reactome: R-HSA-9027277 Reactome: R-HSA-9027283 Reactome: R-HSA-9027284 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Erythropoietin protein Epoetin protein EPO protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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