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產(chǎn)品詳情

  • 產(chǎn)品名稱：Human ErbB-3/HER3 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002155)

  • 產(chǎn)品型號(hào)：STJP002155-100
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡單介紹：
Human ErbB-3/HER3 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002155)
詳情介紹：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human ErbB-3/HER3-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ERBB3
Gene ID: 2065
Uniprot ID: ERBB3_HUMAN
Immunogen Region: Ser20-Thr643
Immunogen: Biotinylated Recombinant Human ErbB3/Her3 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Ser20-Thr643) of Human ErbB3/Her3 fused with a His and Avi tag at the C-terminal.
Post Translational Modifications Autophosphorylated. Ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase.
Function Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it.ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation.
Protein Name Receptor Tyrosine-Protein Kinase Erbb-3
Proto-Oncogene-Like Protein C-Erbb-3
Tyrosine Kinase-Type Cell Surface Receptor Her3
Database Links Reactome: R-HSA-1227986 P21860-1
Reactome: R-HSA-1236394 P21860-1
Reactome: R-HSA-1250196 P21860-1
Reactome: R-HSA-1257604 P21860-1
Reactome: R-HSA-1306955 P21860-1
Reactome: R-HSA-1358803 P21860-1
Reactome: R-HSA-1963642 P21860-1
Reactome: R-HSA-2219530 P21860-1
Reactome: R-HSA-5673001 P21860-1
Reactome: R-HSA-6785631 P21860-1
Reactome: R-HSA-6811558 P21860-1
Reactome: R-HSA-8847993 P21860-1
Reactome: R-HSA-8863795 P21860-1
Reactome: R-HSA-9664565 P21860-1
Reactome: R-HSA-9665686 P21860-1
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Alternative Protein Names Receptor Tyrosine-Protein Kinase Erbb-3 protein
Proto-Oncogene-Like Protein C-Erbb-3 protein
Tyrosine Kinase-Type Cell Surface Receptor Her3 protein
ERBB3 protein
HER3 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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