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產品詳情

  • 產品名稱：E2F4 Positive Control for STJ500826 peptide (STJ504031)

  • 產品型號：STJ504031-5
  • 產品廠商：ST john's laboratory
  • 產品文檔：
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簡單介紹：
E2F4 Positive Control for STJ500826 peptide (STJ504031)
詳情介紹：
Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: E2F4 Positive Control for STJ500826 is synthetically produced from the 360-410 sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: E2f4
Gene ID: 104394
Uniprot ID: E2F4_MOUSE
Immunogen Region: 360-410
Specificity: This is positive control is recommended for use in combination with E2F4 antibody STJ500826.
Immunogen: Synthetic peptide taken within amino acid region 360-410 on mouse E2F4 protein.
Post Translational Modifications Differentially phosphorylated in vivo.
Function Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTCCGCGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
Peptide Name Transcription Factor E2f4
E2f-4
Database Links Reactome: R-MMU-1538133
Reactome: -MMU-2173796
Reactome: -MMU-69231
Cellular Localisation Nucleus
Alternative Peptide Names Transcription Factor E2f4 protein
E2f-4 protein
E2f4 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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