產(chǎn)品詳情
簡單介紹:
Dystrophin Positive Control for STJ507808 peptide (STJ507811)
詳情介紹:
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Dystrophin Positive Control for STJ507808 is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | DMD |
Gene ID: | 1756 |
Uniprot ID: | DMD_HUMAN |
Specificity: | This is positive control is recommended for use in combination with Dystrophin antibody STJ507808. |
Immunogen: | Partially purified rat aquaporin 7 protein. |
Function | Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission. |
Peptide Name | Dystrophin |
Database Links | Reactome: R-HSA-3000171 Reactome: R-HSA-390522 |
Cellular Localisation | Cell Membrane Sarcolemma Peripheral Membrane Protein Cytoplasmic Side Cytoplasm Cytoskeleton Postsynaptic Cell Membrane In Muscle Cells Sarcolemma Localization Requires The Presence Of Ank2 While Localization To Costameres Requires The Presence Of Ank3 Localizes To Neuromuscular Junctions (Nmjs) In Adult Muscle Nmj Localization Depends Upon Ank2 Presence But Not In Newborn Animals |
Alternative Peptide Names | Dystrophin protein DMD protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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