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產(chǎn)品名稱：Human EGF protein (Active Recombinant) (C-hFc&His) (STJP001110)
產(chǎn)品型號：STJP001110
產(chǎn)品廠商：ST john's laboratory
產(chǎn)品文檔：

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Human EGF protein (Active Recombinant) (C-hFc&His) (STJP001110)

詳情介紹：

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Active Recombinant-Human EGF-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity:	Measured by its ability to stimulate EGF Receptor autophosphorylation in A431 cells.1-10 ng/mL of Recombinant Human EGF can effectively enhance EGF Receptor autophosphorylation.2. Measured by its binding ability in a functional ELISA. Immobilized Hum

Gene Symbol:	EGF
Gene ID:	1950
Uniprot ID:	EGF_HUMAN
Immunogen Region:	Asn 971-Arg 1023
Immunogen:	Recombinant Human EGF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asn 971-Arg 1023) of human EGF (Accession #NP_001954.2) fused with hFc, 6×His tag at the C-terminus.

Tissue Specificity	Expressed in kidney, salivary gland, cerebrum and prostate.
Post Translational Modifications	O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor).
Function	EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro.
Protein Name	Pro-Epidermal Growth Factor Egf Cleaved Into - Epidermal Growth Factor Urogastrone
Database Links	Reactome: R-HSA-114608 Reactome: R-HSA-1227986 Reactome: R-HSA-1236382 Reactome: R-HSA-1236394 Reactome: R-HSA-1250196 Reactome: R-HSA-1251932 Reactome: R-HSA-1257604 Reactome: R-HSA-177929 Reactome: R-HSA-179812 Reactome: R-HSA-180292 Reactome: R-HSA-180336 Reactome: R-HSA-182971 Reactome: R-HSA-1963640 Reactome: R-HSA-1963642 Reactome: R-HSA-212718 Reactome: R-HSA-2219530 Reactome: R-HSA-5637810 Reactome: R-HSA-5638303 Reactome: R-HSA-5673001 Reactome: R-HSA-6785631 Reactome: R-HSA-6811558 Reactome: R-HSA-8847993 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 Reactome: R-HSA-8863795 Reactome: R-HSA-9009391 Reactome: R-HSA-9013507 Reactome: R-HSA-9634638 Reactome: R-HSA-9664565 Reactome: R-HSA-9665348 Reactome: R-HSA-9665686
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Pro-Epidermal Growth Factor protein Egf Cleaved Into - Epidermal Growth Factor protein Urogastrone protein EGF protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產(chǎn)品名稱：Human EGF protein (Active Recombinant) (C-hFc&amp;His) (STJP001110)

產(chǎn)品名稱：Human EGF protein (Active Recombinant) (C-hFc&His) (STJP001110)