產(chǎn)品詳情
簡(jiǎn)單介紹:
Anti-ACHE antibody (C-Term) (STJ70663)
詳情介紹:
Host: | Goat |
Applications: | Pep-ELISA/WB/IF/FC |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-ACHE (C-Term) is suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | WB-0.3-1μg/ml IF-Strong expression of the protein seen in the cytoplasm and nucleus of U2OS cells. 10μg/ml ELISA-antibody detection limit dilution 1:64000. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | ACHE |
Gene ID: | 43 |
Uniprot ID: | ACES_HUMAN |
Immunogen Region: | C-Term |
Accession Number: | NP_000656.1; NP_001269378.1 |
Specificity: | This antibody is expected to recognise isoform NP_000656.1 only (the ubiquitously expressed, hydrophillic form). |
Immunogen Sequence: | QFDHYSKQDRCSDL |
Function | Hydrolyzes rapidly the acetylcholine neurotransmitter released into the synaptic cleft allowing to terminate the signal transduction at the neuromuscular junction. Role in neuronal apoptosis. |
Protein Name | Acetylcholinesterase Ache |
Database Links | Reactome: R-HSA-112311 Reactome: R-HSA-1483191 Reactome: R-HSA-422085 |
Cellular Localisation | Synapse Secreted Cell Membrane Peripheral Membrane Protein Isoform T: Nucleus Only Observed In Apoptotic Nuclei Isoform H: Cell Membrane Lipid-Anchor Gpi-Anchor Extracellular Side |
Alternative Antibody Names | Anti-Acetylcholinesterase antibody Anti-Ache antibody Anti-ACHE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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