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產品詳情
  • 產品名稱:Human DNAM-1/CD226 protein (Recombinant) (C-hFc&His) (STJP001052)

  • 產品型號:STJP001052
  • 產品廠商:ST john's laboratory
  • 產品文檔:
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簡單介紹:
Human DNAM-1/CD226 protein (Recombinant) (C-hFc&His) (STJP001052)
詳情介紹:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human DNAM-1/CD226-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human CD226 at 2 Mu g/mL (100 Mu L/well) can bind Recombinant Human CD155 with a linear range of 0.3-1.2 Mu g/mL.
Gene Symbol: CD226
Gene ID: 10666
Uniprot ID: CD226_HUMAN
Immunogen: Recombinant Human DNAM-1/CD226 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Glu19-Asn247) of human CD226 (Accession #NP_006557.2) fused with an Fc, 6×His tag at the C-terminus.
Tissue Specificity Expressed by peripheral blood T-lymphocytes.
Function Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding.
Protein Name Cd226 Antigen
Dnax Accessory Molecule 1
Dnam-1
Cd Antigen Cd226
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Cd226 Antigen protein
Dnax Accessory Molecule 1 protein
Dnam-1 protein
Cd Antigen Cd226 protein
CD226 protein
DNAM1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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