產(chǎn)品詳情
簡單介紹:
Human Complement C1r subcomponent protein (Recombinant) (C-His) (STJP000917)
詳情介紹:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Complement C1r subcomponent-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.106 |
Immunoreactivity: | Measured by its ability to cleave a colorimetric peptide substrate, N-carbobenzyloxy-Gly-Arg-ThioBenzyl ester (Z-GR-SBzl) , in the presence of 5, 5 Dithio-bis (2-nitrobenzoic acid) (DTNB). The specific activity is >2828 pmol/min/Mu g, asMeasured unde |
Gene Symbol: | C1R |
Gene ID: | 715 |
Uniprot ID: | C1R_HUMAN |
Immunogen Region: | Met1-Asp705 |
Immunogen: | Recombinant Human Complement C1r subcomponent Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Asp705) of human Complement C1r subcomponent (Accession #NP_001724.3) fused with a 6×His tag at t |
Post Translational Modifications | The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. |
Function | C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. |
Protein Name | Complement C1r Subcomponent Complement Component 1 Subcomponent R Cleaved Into - Complement C1r Subcomponent Heavy Chain - Complement C1r Subcomponent Light Chain |
Database Links | Reactome: R-HSA-166663 Reactome: R-HSA-173623 Reactome: R-HSA-977606 |
Cellular Localisation | Secreted |
Alternative Protein Names | Complement C1r Subcomponent protein Complement Component 1 Subcomponent R Cleaved Into - Complement C1r Subcomponent Heavy Chain - Complement C1r Subcomponent Light Chain protein C1R protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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