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產(chǎn)品詳情
  • 產(chǎn)品名稱:Human Coagulation factor III/CD142 protein (Recombinant) (C-His) (STJP000888)

  • 產(chǎn)品型號:STJP000888
  • 產(chǎn)品廠商:ST john's laboratory
  • 產(chǎn)品文檔:
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簡單介紹:
Human Coagulation factor III/CD142 protein (Recombinant) (C-His) (STJP000888)
詳情介紹:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Coagulation factor III/CD142-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Human CD142 at 1 Mu g/mL (100 Mu L/well) can bind Human Tissue Factor Rabbit mAb with a linear range of 0.98-61.71 ng/mL.2. Measured by its ability to activate Coagulation Factor VII
Gene Symbol: F3
Gene ID: 2152
Uniprot ID: TF_HUMAN
Immunogen: Recombinant Human Coagulation factor III/CD142 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly34-Glu251) of human Coagulation Factor III/Tissue Factor/CD142 (Accession #NP_001984.1) fused with
Tissue Specificity Lung, placenta and pancreas.
Function Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The TF:VIIa complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
Protein Name Tissue Factor
Tf
Coagulation Factor Iii
Thromboplastin
Cd Antigen Cd142
Database Links Reactome: R-HSA-140834
Reactome: R-HSA-9031628
Cellular Localisation Isoform 1: Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Alternative Protein Names Tissue Factor protein
Tf protein
Coagulation Factor Iii protein
Thromboplastin protein
Cd Antigen Cd142 protein
F3 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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