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產(chǎn)品詳情

  • 產(chǎn)品名稱：Human Claudin-4 protein (Recombinant) (No tag) (STJP002491)

  • 產(chǎn)品型號(hào)：STJP002491-100
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Human Claudin-4 protein (Recombinant) (No tag) (STJP002491)
詳情介紹：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Claudin-4-No tag protein was developed from hek293 cells and has a target region of No tag. For use in research applications.
Formulation: Supplied as 0.22 Mu m filtered solution in PBS (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Endotoxin: Less than 1EU per Mu g by the LAL method.
Immunoreactivity: Immobilized Human Claudin-4 VLP at 1 Mu g/ml (100 Mu l/well) on the plate. Dose response curve for Anti-Claudin 4 Antibody, hFc Tag with the EC50 of 18.4ng/ml determined by ELISA.
Gene Symbol: CLDN4
Gene ID: 1364
Uniprot ID: CLD4_HUMAN
Immunogen Region: Met1-Val209
Immunogen: Recombinant Human Claudin-4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Val209) of human Claudin-4 (Accession #NP_001296.1) fused with no additional amino acid.
Function Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Protein Name Claudin-4
Clostridium Perfringens Enterotoxin Receptor
Cpe-R
Cpe-Receptor
Williams-Beuren Syndrome Chromosomal Region 8 Protein
Database Links Reactome: R-HSA-420029
Cellular Localisation Cell Junction
Tight Junction
Cell Membrane
Multi-Pass Membrane Protein
Cldn4 Is Required For Tight Junction Localization In The Kidney
Alternative Protein Names Claudin-4 protein
Clostridium Perfringens Enterotoxin Receptor protein
Cpe-R protein
Cpe-Receptor protein
Williams-Beuren Syndrome Chromosomal Region 8 Protein protein
CLDN4 protein
CPER protein
CPETR1 protein
WBSCR8 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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