產(chǎn)品詳情
簡單介紹：
Anti-Acetyl-TAL1-Lys37 antibody (STJ97700)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Acetyl-T-cell acute lymphocytic leukemia protein 1-Lys37 is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TAL1 |
| Gene ID: | 6886 |
| Uniprot ID: | TAL1_HUMAN |
| Specificity: | Acetyl-TAL1/2 (K221/K222/K36/K37) Polyclonal Antibody detects endogenous levels of TAL1/2 around the acetylation site of K221 protein. |
| Immunogen: | Synthesized acetyl-peptide derived from the human TAL1/2 around the acetylation site of K221. |
| Post Translational Modifications | Phosphorylated on serine residues. Phosphorylation of Ser-122 is strongly stimulated by hypoxia. Ubiquitinated.subsequent to hypoxia-dependent phosphorylation of Ser-122, ubiquitination targets the protein for rapid degradation via the ubiquitin system. This process may be characteristic for microvascular endothelial cells, since it could not be observed in large vessel endothelial cells. |
| Function | Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation. |
| Protein Name | T-Cell Acute Lymphocytic Leukemia Protein 1 Tal-1 Class A Basic Helix-Loop-Helix Protein 17 Bhlha17 Stem Cell Protein T-Cell Leukemia/Lymphoma Protein 5 |
| Database Links | Reactome: R-HSA-8939236 Reactome: R-HSA-9616222 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-T-Cell Acute Lymphocytic Leukemia Protein 1 antibody Anti-Tal-1 antibody Anti-Class A Basic Helix-Loop-Helix Protein 17 antibody Anti-Bhlha17 antibody Anti-Stem Cell Protein antibody Anti-T-Cell Leukemia/Lymphoma Protein 5 antibody Anti-TAL1 antibody Anti-BHLHA17 antibody Anti-SCL antibody Anti-TCL5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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