產(chǎn)品詳情
簡單介紹：
Anti-Acetyl-NRIP1-Lys158 antibody (STJ97698)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Acetyl-Nuclear receptor-interacting protein 1-Lys158 is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 IHC-P 1:50-300 ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NRIP1 |
| Gene ID: | 8204 |
| Uniprot ID: | NRIP1_HUMAN |
| Specificity: | Acetyl-RIP140 (K158) Polyclonal Antibody detects endogenous levels of RIP140 around the acetylation site of K158 protein. |
| Immunogen: | Synthesized acetyl-peptide derived from the human RIP140 around the acetylation site of K158. |
| Function | Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors. Positive regulator of the circadian clock gene expression: stimulates transcription of BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC. Involved in the regulation of ovarian function. Plays a role in renal development. |
| Protein Name | Nuclear Receptor-Interacting Protein 1 Nuclear Factor Rip140 Receptor-Interacting Protein 140 |
| Database Links | Reactome: R-HSA-3899300 Reactome: R-HSA-400253 Reactome: R-HSA-9018519 Reactome: R-HSA-9029558 Reactome: R-HSA-9632974 Reactome: R-HSA-9707616 |
| Cellular Localisation | Nucleus Localized To Discrete Foci And Redistributes To Larger Nuclear Domains Upon Binding To Ligand-Bound Nr3c1 |
| Alternative Antibody Names | Anti-Nuclear Receptor-Interacting Protein 1 antibody Anti-Nuclear Factor Rip140 antibody Anti-Receptor-Interacting Protein 140 antibody Anti-NRIP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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