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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-Acetyl-MYB-Lys471 antibody (STJA0005978)

  • 產(chǎn)品型號(hào)：STJA0005978
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Anti-Acetyl-MYB-Lys471 antibody (STJA0005978)
詳情介紹：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Acetyl-Transcriptional activator Myb-Lys471 is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MYB
Gene ID: 4602
Uniprot ID: MYB_HUMAN
Specificity: This antibody detects endogenous levels of Human, Mouse c-Myb (Acetyl Lys471)
Immunogen: Synthesized peptide derived from human c-Myb (Acetyl Lys471)
Post Translational Modifications Ubiquitinated.mediated by SIAH1 and leading to its subsequent proteasomal degradation. SUMOylated by TRAF7.leading to MYB transcriptional activity inhibition. Phosphorylated by NLK on multiple sites, which induces proteasomal degradation. Phosphorylated by HIPK1. This phosphorylation reduces MYB transcription factor activity but not MYB protein levels.
Function Transcriptional activator.DNA-binding protein that specifically recognize the sequence 5'-YAACGTG-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
Protein Name Transcriptional Activator Myb
Proto-Oncogene C-Myb
Database Links Reactome: R-HSA-8939236
Reactome: R-HSA-9018519
Reactome: R-HSA-9616222
Reactome: R-HSA-983231
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Transcriptional Activator Myb antibody
Anti-Proto-Oncogene C-Myb antibody
Anti-MYB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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