產(chǎn)品詳情
簡單介紹:
Chimaerin beta 3 Blocking Peptide peptide (STJ503847)
詳情介紹:
Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Chimaerin beta 3 Blocking Peptide is synthetically produced from the 1-100 sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | CHN2 |
Gene ID: | 1124 |
Uniprot ID: | CHIO_HUMAN |
Immunogen Region: | 1-100 |
Immunogen: | Synthetic peptide taken within amino acid region 1-100 on human beta-chimaerin isoform 3 protein. |
Tissue Specificity | Highest levels in the brain and pancreas. Also expressed in the heart, placenta, and weakly in the kidney and liver. Expression is much reduced in the malignant gliomas, compared to normal brain or low-grade astrocytomas. |
Function | GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors. |
Peptide Name | Beta-Chimaerin Beta-Chimerin Rho Gtpase-Activating Protein 3 |
Database Links | Reactome: R-HSA-9013149 |
Cellular Localisation | Membrane Peripheral Membrane Protein |
Alternative Peptide Names | Beta-Chimaerin protein Beta-Chimerin protein Rho Gtpase-Activating Protein 3 protein CHN2 protein ARHGAP3 protein BCH protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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