產(chǎn)品詳情
簡單介紹：
Human CD66b (CEACAM8) protein (Recombinant) (STJP000513)
詳情介紹：
| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Recombinant-Human CD66b (CEACAM8)-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | 0.2 Mu m filtered PBS solution, pH7.2. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/μg (1EU/μg). NA |
| Immunoreactivity: | The activity was tested by immobilized recombinant CD66a (10ug/ml) ability to bind recombinant human CD66b in functional ELISA. NA |
| Gene Symbol: | CEACAM8 |
| Gene ID: | 1088 |
| Uniprot ID: | CEAM8_HUMAN |
| Immunogen Region: | ECD |
| Immunogen: | Optimized DNA sequence encoding extracellular domain of human CD66bincluding a C-terminal 6His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow. |
| Post Translational Modifications | Glycosylated. |
| Function | Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. |
| Protein Name | Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 Cd67 Antigen Carcinoembryonic Antigen Cgm6 Non-Specific Cross-Reacting Antigen Nca-95 Cd Antigen Cd66b |
| Database Links | Reactome: R-HSA-1566977 Reactome: R-HSA-202733 Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor Cell Surface |
| Alternative Protein Names | Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 protein Cd67 Antigen protein Carcinoembryonic Antigen Cgm6 protein Non-Specific Cross-Reacting Antigen Nca-95 protein Cd Antigen Cd66b protein CEACAM8 protein CGM6 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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