產(chǎn)品詳情
簡單介紹:
Human CD34 protein (Recombinant) (C-hFc&His) (STJP001349)
詳情介紹:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human CD34-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Gene Symbol: | CD34 |
Gene ID: | 947 |
Uniprot ID: | CD34_HUMAN |
Immunogen: | Recombinant Human CD34 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser32-Thr290) of human CD34 (Accession #NP_001020280.1) fused with a Fc, 6×His tag at the C-terminus. |
Post Translational Modifications | Highly glycosylated. Phosphorylated on serine residues by PKC. |
Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
Protein Name | Hematopoietic Progenitor Cell Antigen Cd34 Cd Antigen Cd34 |
Database Links | Reactome: R-HSA-198933 P28906-1 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | Hematopoietic Progenitor Cell Antigen Cd34 protein Cd Antigen Cd34 protein CD34 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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