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產(chǎn)品詳情

  • 產(chǎn)品名稱：Human CD32a (FcgRIIa) protein (Recombinant) (STJP000413)

  • 產(chǎn)品型號(hào)：STJP000413
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Human CD32a (FcgRIIa) protein (Recombinant) (STJP000413)
詳情介紹：
Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human CD32a (FcgRIIa)-protein was developed from hek293. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilised 0.2 Mu m filtered PBS solution, pH7.2.
Dilution Range: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL.. It is recommended to add 0.1% BSA for long term storage of reconstituted product.
Storage Instruction: Lyophilized CD32a, as supplied, should be storedat-20°C to-70°C Upon reconstitution, working aliquots may be stored at 2°C-8°C C for one month, or six months at-20C without detectable loss of activity. It is recommended to add 0.1% BSA for long term
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/μg (1EU/μg). NA
Immunoreactivity: 1ug of Immobilized CD32a was tested to bind human IgG2 in a range of 10-200ng/ml. NA
Gene Symbol: FCGR2A
Gene ID: 2212
Uniprot ID: FCG2A_HUMAN
Immunogen Region: ECD
Immunogen: Optimized DNA sequence encoding Human extracellular domain of human CD32aincluding a C-terminal 6His tag was expressed in HEK293 cells. NA
Tissue Specificity Found on monocytes, neutrophils and eosinophil platelets.
Post Translational Modifications Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.
Function Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A
Igg Fc Receptor Ii-A
Cdw32
Fc-Gamma Rii-A
Fc-Gamma-Riia
Fcrii-A
Cd Antigen Cd32
Database Links Reactome: R-HSA-2029481
Reactome: R-HSA-2029482
Reactome: R-HSA-2029485
Reactome: R-HSA-6798695
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A protein
Igg Fc Receptor Ii-A protein
Cdw32 protein
Fc-Gamma Rii-A protein
Fc-Gamma-Riia protein
Fcrii-A protein
Cd Antigen Cd32 protein
FCGR2A protein
CD32 protein
FCG2 protein
FCGR2A1 protein
IGFR2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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