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產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：BMPR1A Blocking Peptide for STJ500281 peptide (STJ505490)

  • 產(chǎn)品型號(hào)：STJ505490-250
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
BMPR1A Blocking Peptide for STJ500281 peptide (STJ505490)
詳情介紹：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: BMPR1A Blocking Peptide for STJ500281 is synthetically produced from the 460-510 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Dilution Range: WB:
IHC: 1:50-1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: BMPR1A
Gene ID: 657
Uniprot ID: BMR1A_HUMAN
Immunogen Region: 460-510
Specificity: This blocking peptide is recommended for use in combination with BMPR1A antibody, STJ500281
Immunogen: Synthetic peptide taken within amino acid region 460-510 on human Bone morphogenetic protein receptor type-1A.
Tissue Specificity Highly expressed in skeletal muscle.
Post Translational Modifications Glycosylated.
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. May promote the expression of HAMP, potentially via its interaction with BMP2.
Peptide Name Bone Morphogenetic Protein Receptor Type-1a
Bmp Type-1a Receptor
Bmpr-1a
Activin Receptor-Like Kinase 3
Alk-3
Serine/Threonine-Protein Kinase Receptor R5
Skr5
Cd Antigen Cd292
Database Links Reactome: R-HSA-201451
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Surface
Alternative Peptide Names Bone Morphogenetic Protein Receptor Type-1a protein
Bmp Type-1a Receptor protein
Bmpr-1a protein
Activin Receptor-Like Kinase 3 protein
Alk-3 protein
Serine/Threonine-Protein Kinase Receptor R5 protein
Skr5 protein
Cd Antigen Cd292 protein
BMPR1A protein
ACVRLK3 protein
ALK3 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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