產(chǎn)品詳情
簡單介紹：
Human B7-H5/Gi24/VISTA protein (Recombinant) (C-His) (STJP001028)
詳情介紹：
| Host: | HEK293 cells |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Recombinant-Human B7-H5/Gi24/VISTA-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
| Gene Symbol: | VSIR |
| Gene ID: | 64115 |
| Uniprot ID: | VISTA_HUMAN |
| Immunogen: | Recombinant Human B7-H5/Gi24/VISTA Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Phe 33-Ala 194 ) of human VISTA/B7-H5/PD-1H (Accession #AAH20568.1) fused with a 6×His tag at the C-terminus. |
| Post Translational Modifications | At the cell surface, may be cleaved by MMP14. N-glycosylated. |
| Function | Immunoregulatory receptor which inhibits the T-cell response. May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. May stimulate MMP14-mediated MMP2 activation. |
| Protein Name | V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation Platelet Receptor Gi24 Stress-Induced Secreted Protein-1 Sisp-1 V-Set Domain-Containing Immunoregulatory Receptor V-Set Immunoregulatory Receptor |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative Protein Names | V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation protein Platelet Receptor Gi24 protein Stress-Induced Secreted Protein-1 protein Sisp-1 protein V-Set Domain-Containing Immunoregulatory Receptor protein V-Set Immunoregulatory Receptor protein VSIR protein C10orf54 protein SISP1 protein VISTA protein PP2135 protein UNQ730 protein PRO1412 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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