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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-ABCC3 antibody (Internal) (STJ72479)

  • 產(chǎn)品型號(hào)：STJ72479-100
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Anti-ABCC3 antibody (Internal) (STJ72479)
詳情介紹：
Host: Goat
Applications: Pep-ELISA
Reactivity: Human/Mouse/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-ABCC3 (Internal) is suitable for use in ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: ABCC3
Gene ID: 8714
Uniprot ID: MRP3_HUMAN
Immunogen Region: Internal
Accession Number: NP_003777.2
Specificity: This antibody is expected to recognize reported isoform 1 (NP_003777.2;) only.
Immunogen Sequence: DTLSNHTDLTDNDP
Function ATP-dependent transporter of the ATP-binding cassette (ABC) family that binds and hydrolyzes ATP to enable active transport of various substrates including many drugs, toxicants and endogenous compound across cell membranes. Transports glucuronide conjugates such as bilirubin diglucuronide, estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4). Transports also various bile salts (taurocholate, glycocholate, taurochenodeoxycholate-3-sulfate, taurolithocholate- 3-sulfate). Does not contribute substantially to bile salt physiology but provides an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes. May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrier (Probable). Can confer resistance to various anticancer drugs, methotrexate, tenoposide and etoposide, by decreasing accumulation of these drugs in cells.
Protein Name Atp-Binding Cassette Sub-Family C Member 3
Canalicular Multispecific Organic Anion Transporter 2
Multi-Specific Organic Anion Transporter D
Moat-D
Multidrug Resistance-Associated Protein 3
Database Links Reactome: R-HSA-159418
Reactome: R-HSA-382556
Reactome: R-HSA-9749641
Reactome: R-HSA-9753281
Cellular Localisation Basolateral Cell Membrane
Multi-Pass Membrane Protein
Basal Cell Membrane
Localized To The Basolateral Membrane Of Enterocytes
Localized To The Basal Membrane Of Sertoli Cells
Alternative Antibody Names Anti-Atp-Binding Cassette Sub-Family C Member 3 antibody
Anti-Canalicular Multispecific Organic Anion Transporter 2 antibody
Anti-Multi-Specific Organic Anion Transporter D antibody
Anti-Moat-D antibody
Anti-Multidrug Resistance-Associated Protein 3 antibody
Anti-ABCC3 antibody
Anti-CMOAT2 antibody
Anti-MLP2 antibody
Anti-MRP3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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