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產(chǎn)品詳情
  • 產(chǎn)品名稱:Alpha Synuclein (SNCA) Antibody

  • 產(chǎn)品型號:abx010381
  • 產(chǎn)品廠商:abbexa
  • 產(chǎn)品文檔:
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簡單介紹:
Alpha Synuclein (SNCA) Antibody
詳情介紹:
alpha synuclein is a member of the synuclein family, which also includes beta and gamma synuclein. Synucleins are abundantly expressed in the brain and alpha and beta synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Two alternatively spliced transcripts of SNCA have been identified. Additional splicing may be present but the full-length nature of these variants has not been determined.

Target Alpha Synuclein (SNCA)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, IHC
Host Mouse
Recommended dilutions ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of SNCA expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P37840 (UniProt, ExPASy)
UniProt Secondary AC A8K2A4, Q13701, Q4JHI3, Q6IAU6
Gene Symbol SNCA
GeneID 6622
OMIM 127750
HGNC 11138
Ensembl ENSG00000145335
Molecular Weight 18 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Alpha Synuclein (SNCA)
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