Alpha Adducin (ADD1) Antibody is a Mouse Monoclonal against Alpha Adducin (ADD1). Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C.

Target	Alpha Adducin (ADD1)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Purified recombinant fragment of human ADD1 (AA: 1-193) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P35611 (UniProt, ExPASy)
UniProt Entry Name	ADDA_HUMAN
Gene Symbol	ADD1
GeneID	118
OMIM	102680
NCBI Accession	NP_001110.2 NM_001119.4
HGNC	243
KEGG	hsa:118
Ensembl	ENSG00000087274
String	9606.ENSP00000264758
Molecular Weight	81 kDa
Buffer	PBS, containing 0.05% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Alpha Adducin (ADD1)