MC2R Antibody is a Rabbit Polyclonal antibody against MC2R. MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.

Target	Adrenocorticotropic Hormone Receptor (MC2R)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human MC2R
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q01718 (UniProt, ExPASy)
UniProt Secondary AC	A8K016, Q3MI45, Q504X6
UniProt Entry Name	ACTHR_HUMAN
Gene Symbol	MC2R
GeneID	4158
NCBI Accession	NP_000520.1
KEGG	hsa:4158
String	9606.ENSP00000333821
Molecular Weight	Calculated MW: 34 kDa Observed MW: 37 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Adrenocorticotropic Hormone Receptor (MC2R)